Pharmaceutical composition as well as preparation method and application thereof

The invention discloses a pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition comprises the following components: a compound as shown in a formula I, hydroxypropyl methyl cellulose, benzalkonium chloride and a pH regulator. The pharmaceu...

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Bibliographische Detailangaben
Hauptverfasser: ZHOU SHENG'AN, CAO CHEN, WU MEIRONG, YU CHUILIANG, XUE YAPING, SU YINGXUE, WANG YANDONG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition comprises the following components: a compound as shown in a formula I, hydroxypropyl methyl cellulose, benzalkonium chloride and a pH regulator. The pharmaceutical composition can be used for preparing medicines for preventing or treating cataract. The pharmaceutical composition has good illumination and high-temperature stability, can be stored at room temperature, is convenient for a patient to use, has pH and osmotic pressure close to those of an intraocular environment, is uniform in particle size distribution, and can provide good comfort for the patient. 一种药物组合物及其制备方法和应用。所述药物组合物包括如下组分:式I所示化合物、羟丙基甲基纤维素、苯扎氯铵和pH调节剂。所述药物组合物可用于制备预防或治疗白内障的药物。所述药物组合物具有良好的光照和高温稳定性,可以室温保存,便于患者使用,其pH、渗透压接近眼内环境,粒度分布均匀,能够给予患者良好的舒适性。