Treatment of viral infection related symptoms using c1 esterase inhibitors

The claimed invention relates to the treatment of virus-associated neurological symptoms, in particular to methods of treating such symptoms by administering a complement inhibitor. The types of virus-related neurological symptoms that can be treated according to the invention include extreme fatigu...

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Hauptverfasser: GIANNETTI BRUNO, MELAMED IDO, ROELAND, ARNAUD
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The claimed invention relates to the treatment of virus-associated neurological symptoms, in particular to methods of treating such symptoms by administering a complement inhibitor. The types of virus-related neurological symptoms that can be treated according to the invention include extreme fatigue, sensory loss such as taste loss, cognitive alteration, epilepsy, tremor and stroke, and may be associated with infection by coronavirus such as SARS-CoV-2. The invention comprises administering a complement inhibitor, which may be a recombinant or purified C1 inhibitor. 要求保护的本发明涉及病毒相关神经病学症状的治疗,特别是通过施用补体抑制剂来治疗此类症状的方法。可以根据本发明治疗的病毒相关的神经病学症状的类型包括极度疲劳、感觉丧失例如味觉丧失、认知改变、癫痫、震颤和卒中,并且可能与冠状病毒例如SARS-CoV-2的感染有关。本发明包括施用补体抑制剂,其可以是重组或纯化的C1抑制剂。