Platycodon grandiflorum exosome and application thereof in preparation of medicine for treating lung diseases

The invention provides a platycodon grandiflorum exosome and application of the platycodon grandiflorum exosome in preparation of a medicine for treating lung diseases. The platycodon grandiflorum exosome which meets the standard and is stable in quality can be obtained through the method, the exosome can be efficiently taken by A549 cells and RAW264.7 cells of the lung, and the platycodon grandiflorum exosome has the biological activity of resisting lung tumor cell proliferation and lung inflammation. It is proved that the platycodon grandiflorum exosome can provide a thought for research and development of new drugs in the aspects of drug targeting, tumor resistance and the like in clinical treatment of lung diseases. 本发明提供了一种桔梗外泌体及其在制备肺系疾病药物中的应用。通过本发明的方法可得到符合标准、质量稳定的桔梗外泌体，且该外泌体可以高效地被肺部的A549细胞、RAW264.7细胞摄取，并且具有抗肺部肿瘤细胞增殖、抗肺部炎症的生物活性，证明桔梗外泌体可为临床治疗肺系疾病中药物靶向及抗肿瘤等方面的新药物研发提供思路。