Diisopropanolamine phenylboronic acid ester hydrogel with enhanced hydrolysis stability and preparation method of diisopropanolamine phenylboronic acid ester hydrogel

A preparation method of the diisopropanolamine phenylboronic acid ester hydrogel comprises the following steps: 1) dissolving a phenylboronic acid group-containing raw material in water, and adjusting the pH value to obtain a mixed solution I; 2) dissolving a raw material containing a diisopropanola...

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Bibliographische Detailangaben
Hauptverfasser:	DAI HONGLIAN, GAO SIYUAN, HUANG YE, XU LIUPAN, KANG HAIFEI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS GENERAL PROCESSES OF COMPOUNDING METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-UP USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS WORKING-UP
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Zusammenfassung:	A preparation method of the diisopropanolamine phenylboronic acid ester hydrogel comprises the following steps: 1) dissolving a phenylboronic acid group-containing raw material in water, and adjusting the pH value to obtain a mixed solution I; 2) dissolving a raw material containing a diisopropanolamine group in water, and adjusting the pH value to obtain a mixed solution II; and 3) blending the mixed solution I and the mixed solution II to obtain the diisopropanolamine phenylboronic acid ester hydrogel with enhanced hydrolytic stability. The diisopropanolamine phenylboronic acid ester hydrogel is prepared by blending the phenylboronic acid group-containing solution and the diisopropanolamine group-containing solution, so that the hydrolytic stability, the mechanical property, the drug slow release capability and other properties of the diisopropanolamine phenylboronic acid ester hydrogel can be improved in multiple levels; the related preparation method is relatively simple, the raw materials are wide in sou