Double-network hydrogel as well as preparation method and application thereof

The invention belongs to the technical field of hydrogel, and particularly relates to double-network hydrogel as well as a preparation method and application thereof. The preparation raw materials of the double-network hydrogel comprise dopamine modified oxidized hyaluronic acid and double-bond carr...

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Hauptverfasser: WU TINGTING, LIM SEUNG-WOONG, ZHENG XIAOFEI, ZHOU XINTING, WANG HUAJUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of hydrogel, and particularly relates to double-network hydrogel as well as a preparation method and application thereof. The preparation raw materials of the double-network hydrogel comprise dopamine modified oxidized hyaluronic acid and double-bond carrier modified collagen; the dopamine modified oxidized hyaluronic acid is obtained by grafting oxidized hyaluronic acid with dopamine; the double-bond carrier modified collagen is obtained by grafting a double-bond carrier with collagen. The collagen and oxidized hyaluronic acid are modified, double bonds and dopamine groups are introduced, a double-network cross-linked structure is formed, the adhesion of the hydrogel is improved, meanwhile, the strength and toughness of the hydrogel can be greatly improved, the double-bond carrier modified collagen is used as a first network for light curing cross-linking, and the double-bond carrier modified collagen is used as a second network for light curing cross-linking. The