Functionalized sodium alginate compound as well as preparation method and application thereof

The invention relates to a functionalized sodium alginate compound as well as a preparation method and application thereof, and the preparation method of the functionalized sodium alginate compound comprises the following steps: adding a carboxyl activator into a sodium alginate aqueous solution, then sequentially adding ammoniated manganese dioxide and aminophenylboronic acid, and respectively carrying out amidation reaction, and purifying to obtain the functional sodium alginate compound. The functionalized sodium alginate compound can be used for preparing the glucose-sensitive microneedle, the glucose-sensitive microneedle comprises the functionalized sodium alginate compound and loaded GOx, and the GOx accounts for 1-2% of the total mass of the microneedle. Compared with the prior art, the glucose-sensitive microneedle prepared by taking the functional sodium alginate compound as the raw material can effectively decompose H2O2 while ensuring the glucose response behavior, so that the side effect caused b