ONOO <-> fluorescent probe with endoplasmic reticulum targeting as well as preparation method and application of ONOO <-> fluorescent probe

The invention discloses an ONOO-fluorescent probe with endoplasmic reticulum targeting and a preparation method and application thereof, and relates to the technical field of in-situ imaging detection in organisms, the aggregation-induced emission endoplasmic reticulum fluorescent probe with a quinoline skeleton is designed and synthesized, and the probe molecule is composed of the quinoline skeleton, a targeting group and a reaction group. The endoplasmic reticulum fluorescent probe provided by the invention has the remarkable advantages of small cytotoxicity, high light stability, good endoplasmic reticulum positioning specificity and the like, can specifically detect ONOO level fluctuation under oxidative stress of the endoplasmic reticulum in vivo, and is not interfered by other biomolecules, enzymes and the like. After the target probe reacts with ONOO-, the obtained aggregation-induced emission endoplasmic reticulum probe is good in light stability, low in cytotoxicity and high in endoplasmic reticu