Preparation method of primary amine

The invention discloses a preparation method of primary amine, and belongs to the field of organic synthesis. The method comprises the following steps: preparing a primary amine compound from halogenated hydrocarbon and an ammonia source, carrying out amino protection on the prepared primary amine compound, washing with a mixed solvent containing water and an organic solvent, and finally removing an amino protecting group. The method can effectively remove the inorganic ammonium salt under the condition that the product yield is not obviously reduced, so that the content of the product is obviously increased. 本发明公开了一种伯胺的制备方法，属于有机合成领域。本发明先利用卤代烃与氨源制备伯胺化合物，然后对制备得到的伯胺化合物进行氨基保护，再使用含有水和有机溶剂的混合溶剂进行洗涤，最后再脱去氨基保护基。本发明方法能够在不明显降低产品收率的情况下，有效除去无机铵盐，从而显著提升产品的含量。