Vinpocetine halogenated hydrocarbon compound as well as preparation method and application thereof

The invention discloses a vinpocetine halogenated hydrocarbon compound as well as a preparation method and application thereof. According to the invention, the 14-site ester group of vinpocetine is reduced into hydroxyl, and the hydroxyl is connected with a halogenated hydrocarbon compound. The inventor finds that the derivative contains a vinpocetine parent structure, retains a basic structure consisting of five rings A, B, C, D and E of vinpocetine, can provide a compound source for biological activity screening, and has important application value for drug screening and pharmaceutical industry. The inventor finds that the skeleton compound has an inhibiting effect on PDE1A, has the pharmacological activity of dilating blood vessels, and can be applied to preparation of anti-cerebral apoplexy drugs. The method has the advantages of simple and easy operation, cheap and easily available raw material synthesis, good air stability, wide applicability, and good compatibility with various halogenated hydrocarbons