Isopropanolamine-containing capsaicin compound as well as preparation method and application thereof

The invention relates to the technical field of medicinal chemistry, in particular to a capsaicin compound containing isopropanolamine and a preparation method and application of the capsaicin compound containing isopropanolamine. The capsaicin compound containing isopropanolamine has a structure as...

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Hauptverfasser: FENG YUMEI, QI PUYING, LIU LIWEI, ZHOU XIANG, WU ZHIBING, YANG SONG, WANG NA, LIANG HONG, ZHANG TAIHONG, XUE WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of medicinal chemistry, in particular to a capsaicin compound containing isopropanolamine and a preparation method and application of the capsaicin compound containing isopropanolamine. The capsaicin compound containing isopropanolamine has a structure as shown in a general formula (I): # imgabs0 #. Different bridge chains are used for connecting two pharmacophores to synthesize a series of isopropanolamine-containing capsaicin derivatives, and the compounds have the effects on plant pathogenic bacteria such as Xanthomonas oryzae pv. Oryzae, Xanthomonas citri, Xanthomonas oryzae pv. Oryzae and Xanthomonas syringae pv. Actinidia; the compound has an excellent inhibition effect on plant pathogenic fungi such as cucumber gray mold, pepper fusarium wilt, sclerotinia rot of colza, eggplant verticillium wilt, wheat scab, potato late blight, blueberry root rot, botryosphaeria dothidea, pitaya anthracnose or rice sheath blight disease, and provides an important scientific