Application of glucosamine

The invention discloses an application of glucosamine. The glucosamine and/or the derivative of the glucosamine or the pharmaceutically acceptable salt of the glucosamine are/is applied to preparation of drugs for treating anti-stress diseases. According to the invention, chronic unpredictable mild stress and subcutaneous injection corticosterone models are adopted to explore the action mechanism of glucosamine in stress resistance; experiments prove that after the glucosamine is given for 14-21 days, the opening time percentage, the opening frequency percentage and the preference index for a new object of a subcutaneous injection corticosterone model mouse can be improved; after the glucosamine is given for 7-28 days, the tail suspension immobility time of a CUMS model mouse can be shortened, the preference index on a new object is improved, and the glucosamine is prompted to be capable of improving anxiety, depression-like emotion and cognitive impairment of the model mouse and have an anti-stress effect. 本