Application of substance for detecting RIPKI in preparation of kit for diagnosing CKD-related vascular diseases
The invention discloses an application of a substance for detecting RIPKI in preparation of a kit for diagnosing CKD-related vascular diseases. The substance for detecting the RIPKI comprises primers as shown in SEQ ID NO. 1 to SEQ ID NO. 4; relates to the technical field of chronic kidney disease r...
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Zusammenfassung: | The invention discloses an application of a substance for detecting RIPKI in preparation of a kit for diagnosing CKD-related vascular diseases. The substance for detecting the RIPKI comprises primers as shown in SEQ ID NO. 1 to SEQ ID NO. 4; relates to the technical field of chronic kidney disease related cardiovascular disease diagnosis. Differential expression genes of patients suffering from chronic kidney disease cardiovascular events are obtained through early-stage screening, it is found that expression of RIPK1 in chronic kidney diseases is obviously increased, the expression level of RIPK1 is in negative correlation with renal functions and vascular endothelial function states, and the severity of cardiovascular diseases of CKD patients can be reflected to a certain degree. The RIPK1 as a brand-new molecular marker has a certain application prospect in the aspects of prediction and evaluation of disease progression of patients with chronic kidney diseases.
本发明公开了一种检测RIPKI的物质在制备诊断CKD相关血管病的试剂盒中的应用。检测RIP |
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