Biosensor for detecting uranium ions with high sensitivity and high specificity

The invention belongs to the technical field of analysis and detection, discloses a high-sensitivity and high-specificity biosensor for detecting uranium ions, and particularly discloses a uranium ion detection reagent. The detection reagent/biosensor formed based on the four nucleic acid probes DNA...

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Bibliographische Detailangaben
Hauptverfasser: LIU CHENGSHUAI, TONG HUI, CHEN JUNHUA, CHEN MANJIA, LYU YIWEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of analysis and detection, discloses a high-sensitivity and high-specificity biosensor for detecting uranium ions, and particularly discloses a uranium ion detection reagent. The detection reagent/biosensor formed based on the four nucleic acid probes DNA1, DNA2, DNA3 and DNA4 provided by the invention can realize rapid detection of uranium ions, has good accuracy and reliability, can reach a detection limit of 2pM, and can meet the detection requirements of trace uranium ions. Meanwhile, the biosensor has good specificity, other heavy metal ions do not interfere with a detection result, and the anti-interference capability is high. 本发明属于分析检测技术领域,公开了一种高灵敏高特异性检测铀离子的生物传感器,具体公开了一种铀离子的检测试剂。本发明提供基于四种核酸探针DNA1、DNA2、DNA3和DNA4构成的检测试剂/生物传感器可实现对铀离子的快速检测,具有较好的精确度和可靠性,检测限可达2pM,能满足痕量铀离子检测需求。同时,该生物传感器具有很好的特异性,其他重金属离子不会干扰检测结果,抗干扰能力强。