Method for synthesizing 1-trifluoromethyl indole compound by using 2-alkynyl aryl isothiocyanate as raw material

The invention discloses a method for synthesizing a 1-trifluoromethyl indole compound by taking 2-alkynyl aryl isothiocyanate as a raw material, and belongs to the field of organic chemistry. According to the method disclosed by the invention, the o-alkynyl phenylthioisocyanate compound is taken as a substrate, green and easily available silver fluoride is taken as a fluorine source, and under the action of a catalyst, the construction of a 1-trifluoromethylindole skeleton can be realized in one step, so that a target compound is obtained. The method has the advantages of wide substrate applicability, simple and easily available raw materials and low economic cost; in addition, according to the method, synthesis of the target product can be achieved only through 3-10 hours of reaction, the target product can be obtained with the good yield, and the target compound has wide application in the fields of medicines, pesticides, functional materials and the like. 本发明公开了一种以2-炔基芳基异硫氰酸酯为原料合成1-三氟甲基吲哚化合物的方法，属于有机化学领域。本发