Composition grafted with benzocaine and preparation method thereof

The invention provides a composition grafted with benzocaine and a preparation method of the composition. The composition is prepared from sodium hyaluronate grafted with benzocaine, a thickening agent, polyhydric alcohol, a humectant, a preservative and purified water. According to the invention, benzocaine reacts with sodium hyaluronate oxidized by sodium periodate to form sodium hyaluronate benzocaine Schiff base, and the sodium hyaluronate benzocaine Schiff base is added into a lubricant product to achieve the effects of delaying and lubricating. 本发明提供了一种接枝有苯佐卡因的组合物及其制备方法，该组合物由接枝有苯佐卡因的透明质酸钠、增稠剂、多元醇、保湿剂、防腐剂及纯化水组成。本发明将苯佐卡因与高碘酸钠氧化后的透明质酸钠反应，形成透明质酸钠苯佐卡因席夫碱，加入润滑剂产品中起到延时及润滑功效。