Application of broad-spectrum antibacterial drug in preparation of anti-cancer drug
The invention belongs to the field of medicines, and particularly relates to application of a broad-spectrum antibacterial drug in preparation of an anti-cancer drug. The broad-spectrum antibacterial drugs, including chlorhexidine hydrochloride, sodium pyrithione, triclocarban, nifuratel and neocona...
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Zusammenfassung: | The invention belongs to the field of medicines, and particularly relates to application of a broad-spectrum antibacterial drug in preparation of an anti-cancer drug. The broad-spectrum antibacterial drugs, including chlorhexidine hydrochloride, sodium pyrithione, triclocarban, nifuratel and neoconazole, are found to be capable of remarkably inhibiting proliferation of cells of various cancers such as colorectal cancer, gastric cancer, liver cancer, cervical cancer, breast cancer and ovarian cancer, and the tumor cell proliferation inhibiting effect of the broad-spectrum antibacterial drugs is superior to that of a clinical common drug pentafluorouracil (5-Fu); good anti-tumor application prospects are realized.
本发明属于医药领域,具体涉及一种广谱抗菌药在制备抗癌药物中的应用。本发明发现广谱抗菌药,包括盐酸氯己定、吡硫钠、三氯卡班、硝呋太尔、新康唑均能够显著抑制结直肠癌、胃癌、肝癌、宫颈癌、乳腺癌、卵巢癌等多种癌症细胞的增殖,其抑制肿瘤细胞增殖的效果优于临床常用药物五氟尿嘧啶(5-Fu),具有良好的抗肿瘤应用前景。 |
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