Application of disulfide reducing agent in preparation of medicine for treating and preventing IgA nephropathy

The invention relates to the technical field of biological medicines, and discloses application of a disulfide reducing agent in preparation of a medicine for treating and preventing IgA nephropathy. The disulfide reducing agent comprises at least one of a mercapto-containing thiol compound, a sulfydryl-containing disulfide as a metabolite, phosphorus trihydride and a derivative thereof. On one hand, the disulfide reducing agent disclosed by the invention can be used for reducing the formation of a circulating IgA compound and reducing kidney deposition of the IgA compound by stabilizing sulfydryl on IgA molecules in a circulatory system of a patient, so that the occurrence of IgA nephropathy is delayed; on the other hand, for IgA compounds deposited in circulation and kidneys, the disulfide compound reducing agent realizes dissolution and removal of the IgA compounds by opening disulfide bonds of the IgA compounds. And moreover, the IgA nephropathy patient is not limited to four types of medicines under the