Extraction method of flavone in folium turpiniae and application of flavone in preparation of medicine for treating prostate cancer
The invention provides an extraction method of flavone in folium turpiniae and application of the flavone in preparation of prostate cancer drugs. Through the methods of grinding, degreasing, enzymolysis, fermentation and the like, the extraction rate of flavone in turpinia arguta leaves is increase...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides an extraction method of flavone in folium turpiniae and application of the flavone in preparation of prostate cancer drugs. Through the methods of grinding, degreasing, enzymolysis, fermentation and the like, the extraction rate of flavone in turpinia arguta leaves is increased, and meanwhile, the anti-cancer activity of the flavone-containing extract is improved; the flavone-containing extract obtained by the method provided by the invention has a relatively strong inhibition effect on proliferation of prostatic cancer PC-3 cells, a theoretical basis can be provided for an anti-tumor effect of turpinia formosana leaf flavone, and development and application of turpinia formosana leaves are promoted.
本发明提供了山香圆叶中黄酮的提取方法及其在制备前列腺癌症药物中的应用;通过研磨、脱脂、酶解、发酵等方法,提高了山香圆叶中黄酮的提取率,同时提高了含黄酮提取物的抗癌活性;本发明提供的方法得到的含黄酮提取物对于前列腺癌PC-3细胞的增殖具有较强的抑制作用,可为山香圆叶黄酮的抗肿瘤作用提供理论依据,促进山香圆叶的开发应用。 |
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