Application of camptothecin derivative in preparation of anti-gastric cancer drugs

The invention belongs to the field of medicines, and particularly relates to application of a camptothecin derivative in preparation of an anti-gastric cancer medicine. In-vitro MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) antitumor activity research accidentally finds that the camptothecin derivative disclosed by the invention has a good inhibition effect on gastric cancer and colorectal cancer cells, particularly has a remarkable inhibition effect on gastric cancer cells, and has a treatment effect superior to that of a clinically common camptothecin medicine topotecan. Therefore, the camptothecin derivative disclosed by the invention can be used for preparing the anti-gastric cancer medicine and has a good application prospect. 本发明属于医药领域，具体涉及一种喜树碱衍生物在制备抗胃癌药物中的应用。本发明通过体外MTT抗肿瘤活性研究意外发现，本申请所述的喜树碱衍生物对胃癌、结直肠癌细胞具有良好的抑制作用，尤其对于胃癌细胞具有显著的抑制效果，其治疗效果优于临床常用喜树碱药物拓扑替康。因此，本申请所述的喜树碱衍生物可用于制备治疗抗胃癌药物，具有良好的应用前景。