Process for production of clavulanic acid and/or salts thereof

Process for production of clavulanic acid and/or salts thereof

A batch fermentation is carried out continuously or semicontinuously using strains of Streptomyces clavuligerus ATCC 27064 or mutants thereof. The fermentation process is carried out with a strict control of the soluble phosphate in the medium, both at the beginning and throughout the process. As a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: M. A. MORENO VALLE, M. J. LOPEZ NIETO, C. RODRIGUEZ OTERO
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A batch fermentation is carried out continuously or semicontinuously using strains of Streptomyces clavuligerus ATCC 27064 or mutants thereof. The fermentation process is carried out with a strict control of the soluble phosphate in the medium, both at the beginning and throughout the process. As a carbon source, lipids, preferably triglycerides can be used. Substantial increases in the production of the antibiotic are obtained.