Anti-CD7 antibody and application thereof

The invention relates to an anti-CD7 antibody and application thereof, the antibody comprises a heavy chain variable region, and the heavy chain variable region comprises CDR1, CDR2 and CDR3. The anti-CD7 antibody only comprises a heavy chain variable region, has high affinity and specificity, can e...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	DI SHENGMENG, ZHU MING, LI ZHAORUN, SHI LEI, MA HENG, ZHAO ZUOSHUN, FAN YANQIU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to an anti-CD7 antibody and application thereof, the antibody comprises a heavy chain variable region, and the heavy chain variable region comprises CDR1, CDR2 and CDR3. The anti-CD7 antibody only comprises a heavy chain variable region, has high affinity and specificity, can efficiently target a CD7 antigen, and is simple in structure and easy to prepare, and the chimeric antigen receptor can efficiently target CD7 by utilizing the anti-CD7 antibody to construct the chimeric antigen receptor. 本发明涉及一种抗CD7抗体及其应用，所述抗体包括重链可变区，所述重链可变区包括CDR1、CDR2和CDR3。本发明的抗CD7抗体仅包括重链可变区，具备高亲和力和特异性，能够高效靶向CD7抗原，且结构简单，易于制备，利用所述抗CD7抗体构建嵌合抗原受体，所述嵌合抗原受体能够高效靶向CD7。