System for detecting neutrophil extracellular trap net and evaluating thrombus risk

The invention discloses a system for detecting a neutrophil extracellular trapping net and evaluating thrombus risk. Through microscopic observation of a peripheral blood sample, the neutrophil extracellular trap net and the neutrophil nuclear granulocyte are identified according to morphological ch...

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Bibliographische Detailangaben
Hauptverfasser: YANG HAILIN, QIN YU, MA JINGYUN, WANG QIONG, ZHOU KEHAO, XIE LI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a system for detecting a neutrophil extracellular trapping net and evaluating thrombus risk. Through microscopic observation of a peripheral blood sample, the neutrophil extracellular trap net and the neutrophil nuclear granulocyte are identified according to morphological characteristics of the cells, and the severity of thrombosis and even the risk of death are evaluated through quantitative analysis of the ratio of the neutrophil extracellular trap net. The method disclosed by the invention can be semi-automatic, the operation steps are few, the consumed time is short, and a quantitative result can be quickly obtained within 10 minutes; the method is high in stability degree, the NETs in each stage can be accurately identified, and the illness state of a patient can be more accurately evaluated. 本文公开了一种检测中性粒细胞胞外诱捕网、评估血栓风险的系统。本发明通过对外周血样的显微观测,根据细胞的形态特征鉴定出中性粒细胞胞外诱捕网和中性分叶核粒细胞,并通过定量分析中性粒细胞胞外诱捕网的比率来评估血栓形成的严重程度,甚至死亡风险。本文公开的方法可以是(半)自动化,操作步骤少,耗时短,在10min内快速得到定量结果;本法稳定程度高,对各阶段的NETs都有准确的鉴别,可以更准