Embolization microsphere and preparation method thereof
The invention discloses embolism microspheres and a preparation method thereof. The method comprises the following steps: S1, preparing a polyvinyl alcohol macromonomer; s2, preparing a water phase; s3, preparing an oil phase; step S4, carrying out a cross-linking reaction on the water phase prepare...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses embolism microspheres and a preparation method thereof. The method comprises the following steps: S1, preparing a polyvinyl alcohol macromonomer; s2, preparing a water phase; s3, preparing an oil phase; step S4, carrying out a cross-linking reaction on the water phase prepared in the step S2 and the oil phase prepared in the step S3 to obtain polyvinyl alcohol hydrogel microspheres; step S5, washing and screening the polyvinyl alcohol hydrogel microspheres prepared in the step S4; and step S6, drying the hydrogel microspheres screened in the step S5 to prepare the polyvinyl alcohol embolization microspheres. Compared with the prior art, the size of the microspheres can reach the micron level; balls are easy to form and high in toughness; the particle size can be controlled by adjusting the concentration of the monomer solution, the oil-water ratio, the dosage of the cross-linking agent, the rotating speed and the like. The reaction process of the reversed-phase suspension polymerizatio |
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