Pharmaceutical composition containing radix scrophulariae or extract of radix scrophulariae and application of pharmaceutical composition

According to the pharmaceutical composition containing the radix scrophulariae or the extract thereof and the application of the pharmaceutical composition, compared with a formula composed of honeysuckle, the radix scrophulariae, angelica sinensis and liquorice, the single medicine or active compon...

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Hauptverfasser: ZENG HUI, GAO YAN, MA YALUAN, JIE SHANSHAN, ZHANG JU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:According to the pharmaceutical composition containing the radix scrophulariae or the extract thereof and the application of the pharmaceutical composition, compared with a formula composed of honeysuckle, the radix scrophulariae, angelica sinensis and liquorice, the single medicine or active components of the pharmaceutical composition can reduce migration of neutrophils by adjusting the activity of the neutrophils, so that the curative effect of the radix scrophulariae is improved, and the curative effect of the radix scrophulariae is improved. The immune injury caused by improperly activated neutrophil is relieved, and the joint injury of acute gouty arthritis (AGA) model mice, collagen antibody induced arthritis (CAIA) model mice and collagen induced arthritis (CIA) model mice is effectively relieved. It is further proved that a new strategy for treating diseases related to abnormal activation of neutrophil by targeting neutrophil is feasible. 本发明提供一种含玄参或其提取物的药物组合物及其用途,与由金银花、玄参、当归和甘草组成的组方相比,本发明的单药或其活性组分能够