Application of perennial sowthistle polysaccharide extract in prevention and treatment of ulcerative colitis

The invention discloses application of a perennial sowthistle polysaccharide extract in prevention and treatment of ulcerative colitis, and belongs to the technical field of medicines. The perennial sowthistle polysaccharide extract disclosed by the invention can be used for effectively treating or...

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Hauptverfasser: ZHOU YULONG, HOU SHENGHUA, REN YACHAO, SUI YILEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of a perennial sowthistle polysaccharide extract in prevention and treatment of ulcerative colitis, and belongs to the technical field of medicines. The perennial sowthistle polysaccharide extract disclosed by the invention can be used for effectively treating or relieving the symptoms of ulcerative colitis, including weight change, colon shortening, DAI score, pathological injury and the like; blood routine results show that the sonchus brachyotus polysaccharide extract improves blood routine parameters of DSS-induced enteritis mice; immune experiment results show that the sonchus brachyotus polysaccharide extract can regulate immune parameters; 16S rRNA (ribosomal Ribonucleic Acid) detection results show that after the sonchus brachyotus polysaccharide extract is used for treatment, the intestinal microflora composition among the groups has obvious difference; the metabonomics research result shows that the sonchus brachyotus polysaccharide extract can regulate the metabo