Method for producing L-amino acid

Provided is a method for producing an L-amino acid such as L-glutamic acid. In the present invention, an L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability in a culture medium and collecting an L-amino acid from t...

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Bibliographische Detailangaben
Hauptverfasser: ONO, YUKIKO, ITO YOSHIHIRO, ISHIDA, RIHITO, HAMANO CHIE, INOUE KOTA, ONISHI FUMITO, HARA YOSHIHIKO, EBARA NAOKI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided is a method for producing an L-amino acid such as L-glutamic acid. In the present invention, an L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability in a culture medium and collecting an L-amino acid from the culture medium and/or a cell of the bacterium. The bacterium has been modified so as to have one or more modifications selected from the group consisting of modifications (A) to (F): (A) a modification in which the activity of a BudA protein is reduced; (B) a modification in which the activity of the BudB protein is reduced; (C) a modification in which the activity of the BudC protein is reduced; (D) a modification in which the activity of the PAJ3461 protein is reduced; (E) a modification in which the activity of the PAJ3462 protein is reduced; and (F) a modification in which the activity of the PAJ3463 protein is reduced. 本发明提供一种L-谷氨酸等L-氨基酸的制造方法。本发明中,在培养基中培养属于肠杆菌科并且具有L-氨基酸生产能力的细菌,从该培养基和/或该细菌的菌体中采集L-氨基酸,由此制造L-氨