Preparation method of alpinia oxyphylla alcohol extract and application of alpinia oxyphylla alcohol extract in preparation of diabetes drugs

The invention belongs to the technical field of southern drugs, discloses a preparation method of alpinia oxyphylla alcohol extract and application of the alpinia oxyphylla alcohol extract in preparation of drugs for treating and/or preventing diabetes related diseases, and particularly relates to a...

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Hauptverfasser: HE PEIXIA, WANG YINGHUAN, XU JIAN, ZHOU MINGYAN, ZHU ZHE, LIAN XIUXIA, WANG GAO'AN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of southern drugs, discloses a preparation method of alpinia oxyphylla alcohol extract and application of the alpinia oxyphylla alcohol extract in preparation of drugs for treating and/or preventing diabetes related diseases, and particularly relates to application of the alpinia oxyphylla alcohol extract in preparation of drugs for treating and/or preventing diabetes related diseases. According to the invention, an IR-HepG2 cell model is constructed, and the effect of alpinia oxyphylla alcohol extract in improving IR and glycometabolism is explored. Results show that after the IR-HepG2 cells incubate the alcohol extracts with different concentrations, the glucose intake and consumption of the IR-HepG2 cells are remarkably improved, the balance of glucose inside and outside the cells is maintained, and it is proved that the alpinia oxyphylla alcohol extract, one of the four southern drugs, can play the effect of reducing blood sugar by improving the IR effect; furt