Staple peptide and method thereof

The present disclosure provides, inter alia, a variety of available agents. In some embodiments, the provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides techniques for modulating beta-catenin function. In some embodiments, the present disclosure provides te...

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Bibliographische Detailangaben
Hauptverfasser: WHITE BRIAN HALBERT, LING KEVIN, SANDUKE LA DANIEL, VERDINE GREGORY L, ORTET PAULA CRISTINA, MCGEE JOHN HANNEY, HOOROFF, JONATHAN, BARRY, LI ZHI, SI YAGUANG, ALFARO-LOPEZ LORENZO JOSUE, CAPUCCI SARAH ISABEL, DU PEICHENG, TREMBLAY MARTIN ROBERT
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure provides, inter alia, a variety of available agents. In some embodiments, the provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides techniques for modulating beta-catenin function. In some embodiments, the present disclosure provides techniques for the prevention and/or treatment of a condition, disorder or disease associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids and agents that can provide improved properties and/or activity. 本公开内容尤其提供了多种可用的药剂。在一些实施方案中,所提供药剂可与β-联蛋白结合。在一些实施方案中,本公开内容提供了用于调节β-联蛋白功能的技术。在一些实施方案中,本公开内容提供了用于预防和/或治疗与β-联蛋白相关的病症、障碍或疾病的技术。在一些实施方案中,本公开内容提供了可提供改善的特性和/或活性的经设计氨基酸和药剂。