Application of transmembrane transporter as growth regulation switch in genetically engineered bacteria

The invention provides an application of transmembrane transporter NPF/SWEET as a growth regulation switch in genetically engineered bacteria, which is characterized in that a coding gene of the transmembrane transporter is introduced into the genetically engineered bacteria, and the transmembrane transporter is induced and expressed at a proper time, so that the growth of the strain is inhibited or dead; the gene engineering bacteria can be cleaned or the growth of the gene engineering bacteria is limited, the potential risk of escaping of the gene engineering bacteria is reduced, the safety management work of the gene engineering bacteria can be further enhanced, and meanwhile, the cell catalytic reaction process can be indirectly regulated and controlled through growth regulation and control. 本发明提供了一种跨膜转运蛋白NPF/SWEET作为生长调控开关在基因工程菌中的应用，通过在基因工程菌中引入跨膜转运蛋白的编码基因并在适当时机诱导表达该跨膜转运蛋白，使得菌株生长受到抑制或者死亡，以完成对基因工程菌的清除或限制生长，减少其外逸的潜在危险性，有助于进一步加强基因工程菌的安全管理工作，同时可通过生长调控间接调控细胞催化反应进程。