Biodegradable styptic powder containing recombinant human thrombin as well as preparation method and application of biodegradable styptic powder

The invention relates to the technical field of medical materials, in particular to biodegradable styptic powder containing recombinant human thrombin as well as a preparation method and application of the biodegradable styptic powder. The biodegradable styptic powder provided by the invention is pr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MA WENDI, LYU BINHUA, SHENG ZELIN, SUN WANYING, LYU DONG, LIU RUIFENG, ZHAO YANFU
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the technical field of medical materials, in particular to biodegradable styptic powder containing recombinant human thrombin as well as a preparation method and application of the biodegradable styptic powder. The biodegradable styptic powder provided by the invention is prepared from the following components: thrombin, a crosslinking matrix, sodium alginate and/or sodium hyaluronate and sodium carboxymethyl starch, the biodegradable styptic powder disclosed by the invention has good biocompatibility and extremely strong adsorption capacity and expansion capacity, can rapidly absorb moisture in blood at a bleeding point and enrich and concentrate blood coagulation substances in the blood, so that the bleeding point of a wound surface is rapidly blocked, and a physical compression hemostasis effect is achieved; meanwhile, the recombinant human thrombin loaded in the biodegradable styptic powder can also achieve a better blood coagulation effect, hemostasis is rapid, and the effect is