TRAP1 inhibitors and uses thereof

The present application provides a compound for inhibiting TRAP1 or a pharmaceutically acceptable salt thereof. In this case, the compound, or a pharmaceutically acceptable salt thereof, can inhibit binding between TRAP1 and a customer protein. Furthermore, the present application provides a pharmac...

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Bibliographische Detailangaben
Hauptverfasser:	YUN NAM-KU, KIM SO-YEON, KANG BYUNG HEON
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application provides a compound for inhibiting TRAP1 or a pharmaceutically acceptable salt thereof. In this case, the compound, or a pharmaceutically acceptable salt thereof, can inhibit binding between TRAP1 and a customer protein. Furthermore, the present application provides a pharmaceutical composition for the treatment of cancer or ocular diseases, comprising a compound inhibiting TRAP1 or a pharmaceutically acceptable salt thereof, and uses thereof. 本申请提供了一种抑制TRAP1的化合物或其药学上可接受的盐。在这种情况下，所述化合物或其药学上可接受的盐可以抑制TRAP1与客户蛋白之间的结合。此外，本申请提供了：一种用于治疗癌症或眼部疾病的药物组合物及其用途，所述药物组合物包含抑制TRAP1的化合物或其药学上可接受的盐。