Application of monocyte expressed IL-6 in evaluation of tobacco leaf irritation and method for evaluating tobacco leaf irritation

The invention discloses application of monocyte expressed IL-6 in evaluation of tobacco leaf irritation and a method for evaluating tobacco leaf irritation. The expression level of IL-6 in monocyte is in positive correlation with tobacco leaf irritation. The invention further provides a method for e...

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Hauptverfasser: LAI YANHUA, LIANG YAOXING, ZHANG XI, PAN XIAOWEI, GU ZHENGKUN, WANG HAN, WANG JUNXIA, HUANG JIAJIE, LI JINCHENG, WANG YUSHENG, ZHOU RONG, PENG CHEN, ZHAI SHENG, ZHAN LEI, GAO RENJI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of monocyte expressed IL-6 in evaluation of tobacco leaf irritation and a method for evaluating tobacco leaf irritation. The expression level of IL-6 in monocyte is in positive correlation with tobacco leaf irritation. The invention further provides a method for evaluating the irritation of the tobacco leaves, the irritation of the tobacco leaves to be detected can be judged by measuring the expression level of IL-6 in cells treated by the smoke extract extracted from the tobacco leaves to be detected, and the higher the expression level of IL-6 is, the stronger the irritation of the tobacco leaves is. According to the method, the irritation of the tobacco leaves can be effectively evaluated, the subjectivity of determining the irritation of the tobacco leaves by depending on professional smoke panel test personnel under the current standard is avoided, and meanwhile, the body health of the smoke panel test personnel is guaranteed. 本发明公开了单核细胞表达的IL-6在评价烟叶刺激性中的应用及评价烟叶刺激性的方法,I