High-precision nifedipine controlled release tablet related substance detection method

The invention discloses a high-precision nifedipine controlled release tablet related substance detection method, which comprises: 1, sample preparation: preparing a nifedipine controlled release tablet sample into solid powder, and ensuring that the sample is uniform and has no obvious color difference and odor; 2, spectral measurement: collecting spectral data of the nifedipine controlled release tablet sample by using a near infrared spectrometer; 3, data preprocessing: preprocessing the spectral data obtained by measurement; 4, modeling analysis: establishing a modeling analysis method of principal component regression analysis based on chemometrics, and establishing a quantitative relation model for the spectral data and the content of nifedipine and related components; the method has the beneficial effects that the content of nifedipine and other related components in the sample can be predicted through simple spectral measurement, and compared with a traditional method, the method has the advantages of