Preparation method of alkyl phosphorothioate compound containing quinoxalinone structural unit

The invention belongs to the field of organic synthesis, and particularly discloses a preparation method of an alkyl phosphorothioate compound containing a quinoxaline ketone structural unit, which comprises the following step: reacting a quinoxaline ketone compound, olefin, phosphorothioate and ammonium persulfate in a DMSO (dimethylsulfoxide)-containing solvent to prepare an alkyl phosphorothioate compound product containing the quinoxaline ketone structural unit. The invention provides a brand-new one-pot coupling synthesis strategy of quinoxalinone, olefin and phosphorothioate, and aiming at the problems of high one-pot conversion difficulty, non-ideal selectivity and the like in the brand-new synthesis strategy, substrates of formulas 1-3 and ammonium persulfate are creatively reacted in a DMSO (dimethylsulfoxide) solvent, and on the basis of synergistic combination of ammonium persulfate and DMSO, the yield of the quinoxalinone-olefin-phosphorothioate compound is greatly increased, so that the yield of