Novel ipratropium bromide crystal and preparation method thereof

The invention belongs to the technical field of crystal form drug molecules, and particularly relates to a novel ipratropium bromide crystal and a preparation method thereof. According to the novel ipratropium bromide crystal provided by the invention, Cu-K alpha radiation is adopted, and an X-ray diffraction spectrum represented by 2 theta has diffraction peaks at the positions of 8.76 +/-0.2 degrees, 10.26 +/-0.2 degrees, 12.68 +/-0.2 degrees, 13.75 +/-0.2 degrees, 14.08 +/-0.2 degrees, 15.23 +/-0.2 degrees, 15.59 +/-0.2 degrees, 17.21 +/-0.2 degrees, 18.40 +/-0.2 degrees, 20.30 +/-0.2 degrees, 22.43 +/-0.2 degrees, 25.11 +/-0.2 degrees, 27.37 +/-0.2 degrees and 29.04 +/-0.2 degrees; the new crystal of ipratropium bromide provided by the invention has excellent properties, excellent stability and solubility and lower moisture absorption weight gain, and provides a high-quality raw material choice for preparation production of ipratropium bromide. 本发明属于晶型药物分子技术领域，具体涉及一种异丙托溴铵新晶体及其制备方法。本发明提供的异丙托溴铵新晶体，使用Cu-Kα辐射