Indocyanine near-infrared two-region dye with aggregation-induced emission effect as well as preparation method and application of indocyanine near-infrared two-region dye
The invention discloses an indocyanine near-infrared two-region dye with an aggregation-induced emission effect as well as a preparation method and application of the indocyanine near-infrared two-region dye. The indocyanine near-infrared two-region dye has the following structure: # imgabs0 #. The...
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Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses an indocyanine near-infrared two-region dye with an aggregation-induced emission effect as well as a preparation method and application of the indocyanine near-infrared two-region dye. The indocyanine near-infrared two-region dye has the following structure: # imgabs0 #. The dye has strong ultraviolet absorption and good fluorescence property in a near-infrared two region; the fluorescent probe has the characteristics of large molar extinction coefficient, high aggregation-induced emission effect and high fluorescence quantum efficiency, is good in biocompatibility, and can be used for high-contrast imaging of deep tissue blood vessels of organisms. Besides, the dye with the structure belongs to small organic molecules, has multiple chemical sites, and can be connected with proper tumor targeting molecules through click reaction, so that early-stage high-signal-to-noise-ratio detection tracing of tumor tissues is realized.
本发明公开了一种具有聚集诱导发光效应的吲哚菁近红外二区染料及其制备方法和应用,所述吲哚菁近红外二区染料具有以下结构:#imga |
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