Modified collagen barrier membrane and preparation method thereof
The invention belongs to the technical field of biological material preparation, and particularly relates to a modified collagen barrier membrane and a preparation method thereof. The preparation method provided by the invention comprises the following steps: dissolving type I collagen and poly (L-l...
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| creator | WANG YING HU JINXING CHEN CHAOZHEN YU ZHOU YANG GUOLI ZHANG JING |
| description | The invention belongs to the technical field of biological material preparation, and particularly relates to a modified collagen barrier membrane and a preparation method thereof. The preparation method provided by the invention comprises the following steps: dissolving type I collagen and poly (L-lactide-caprolactone) in a volatile polar solvent to obtain a membrane casting solution; casting the membrane casting solution into a mold to form a membrane, so as to obtain a cross-linked membrane; and immersing the reverse side of the cross-linked membrane in a mineralizing solution for mineralization to obtain the collagen barrier membrane, the mineralizing liquid comprises Ca < 2 + >, polyaspartic acid and HPO4 < 2->. The modified collagen barrier membrane obtained by the preparation method provided by the invention takes type I collagen and poly (L-lactide-caprolactone) as raw materials, so that the cost is reduced, the mechanical property is better, and a stable proliferation space and enough proliferation ti |
| format | Patent |
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The preparation method provided by the invention comprises the following steps: dissolving type I collagen and poly (L-lactide-caprolactone) in a volatile polar solvent to obtain a membrane casting solution; casting the membrane casting solution into a mold to form a membrane, so as to obtain a cross-linked membrane; and immersing the reverse side of the cross-linked membrane in a mineralizing solution for mineralization to obtain the collagen barrier membrane, the mineralizing liquid comprises Ca < 2 + >, polyaspartic acid and HPO4 < 2->. 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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | Modified collagen barrier membrane and preparation method thereof |
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