Application of nicotinic acid to preparation of medicine for relieving pullorum disease of chicks through GPR109A receptor

The invention discloses an application of nicotinic acid in preparation of a medicine for relieving pullorum disease of chicks through a GPR109A receptor, which comprises the following steps: S1, purchasing 60 SPF-level 1-day-old chicks, then dividing the 60 1-day-old chicks into six groups, each group comprising 10 chicks, the method comprises the following steps of: selecting a blank control group, a salmonella pullorum group, a nicotinic acid low-dose treatment group (20mg/kg), a nicotinic acid medium-dose treatment group (60mg/kg), a nicotinic acid high-dose treatment group (80mg/kg) and an antibiotic group, starting to attack bacteria at the age of 1 day, and feeding different doses of nicotinic acid and antibiotics for 14 days at the same time. According to the application, a brand-new dairy cow breast fibrosis tendency relieving strategy is formulated, in-vivo experiments prove that GPR109A plays an important biological function in the occurrence and development process of chicken pullorum disease, and