Oligopeptide as well as application and composition thereof

The present invention relates to an oligopeptide and use and composition thereof, the oligopeptide comprises 2 to 10 amino acids, and the oligopeptide comprises an amino acid sequence of tyrosine-arginine (Tyr-Arg) and/or threonine-serine-lysine (Thr-Ser-Lys). The disclosure further provides a use of the oligopeptide in the preparation of a medicament for treating or preventing bone-related diseases and/or disorders, comprising administering a therapeutically effective amount of oligopeptide to a subject in need thereof. In addition, the invention also provides an oligopeptide composition, which comprises the oligopeptide and a pharmaceutically acceptable carrier. 本发明涉及一种寡肽及其用途及组合物，其包含2至10个氨基酸，其中，该寡肽包含酪氨酸-精氨酸(Tyr-Arg)及/或苏氨酸-丝氨酸-赖氨酸(Thr-Ser-Lys)的氨基酸序列。本公开进一步提供该寡肽在制备治疗或预防骨骼相关的疾病和/或病症的药物中的用途，包括对有需要的受试者给药治疗有效量的寡肽。此外，本公开还提供一种寡肽组合物，其包含该寡肽以及药学上可接受的载体。