Porous hybrid membrane and preparation method of polymyxin B sulfate powder

The invention relates to the technical field of medicines, and particularly discloses a porous hybrid membrane and a preparation method of polymyxin B sulfate powder. The porous hybrid membrane is prepared according to the following steps: (1) adding ZIF-7 nanocrystals and polyaniline into acetonitrile, adding polyisocyanate under a heating condition, and stirring to obtain a modified solution; and (2) dipping a polysulfone membrane substrate in the modification liquid for heat preservation, taking out the polysulfone membrane substrate after heat preservation is finished, airing the polysulfone membrane substrate, and continuously repeating the operations of dipping and airing for three times under the same condition to obtain the porous hybrid membrane. When the porous hybrid membrane is used for filtering the polymyxin B sulfate, the loss of the polymyxin B sulfate can be reduced, the yield of the polymyxin B sulfate can be increased, and the production cost of related medicines of the polymyxin B sulfate