Ackermansiella muciniphila and application thereof

The invention discloses ackermania muciniphila and application thereof, the ackermania muciniphila is named as Akkermania muciniphila in taxonomy, is preserved in China Center for Type Culture Collection on October 16, 2023, and has a preservation number of CCTCC NO: M 20231906, and the ackermania m...

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Bibliographische Detailangaben
Hauptverfasser: SHI YING, LIU XUNZHI, HAN HUAN, CUI WENFENG, YI DEWEI, LIU ZENGLI, XIONG HUI, WU HAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses ackermania muciniphila and application thereof, the ackermania muciniphila is named as Akkermania muciniphila in taxonomy, is preserved in China Center for Type Culture Collection on October 16, 2023, and has a preservation number of CCTCC NO: M 20231906, and the ackermania muciniphila is preserved in China Center for Type Culture Collection on October 16, 2023. The ackermansiella muciniphila disclosed by the invention has relatively good tolerance to acid, cholate, artificial gastric juice and artificial intestinal juice, and an LPS (lipopolysaccharide)-induced RAW 264.7 cell inflammation model shows that the ackermansiella muciniphila disclosed by the invention has an anti-inflammatory effect and can be used for remarkably inhibiting the generation of inflammatory factors NO, IL-6 and IL-1beta; when ackermansiella muciniphila and RAW 264.7 macrophages are co-cultured, a small amount of NO can be generated, but is lower than the secretion amount of NO in an LPS group, which indicates