Dicationic cyanine dye as well as preparation method and application thereof

The invention discloses a dicationic cyanine dye as well as a preparation method and application thereof. The cyanine dye has a structure as shown in a general formula I. The dicationic cyanine dye disclosed by the invention has the characteristics of no heavy atom modification and dicationic property, and has the capabilities of near-infrared first-region absorption and emission, high specific mitochondrial targeting capability, high molar extinction coefficient and high photosensitization efficiency. Under the irradiation of near-infrared light, the compound has excellent tumor cell killing capability and has a good application prospect in anti-tumor treatment. # imgabs0 # 本发明公开了本发明提供一种双阳离子类菁染料及其制备方法和应用，所述菁染料具有通式I的结构。本发明所述的双阳离子类菁染料具有无重原子修饰、双阳离子特性，且具有近红外一区吸收和发射、高特异性线粒体靶向能力、高摩尔消光系数、高效光敏化效率的能力。在近红外光照射下具有优异的肿瘤细胞杀伤能力，在抗肿瘤治疗中具有良好的应用前景。#imgabs0#