Application of alpinia oxyphylla monomer caryophylline in preparation of diabetes medicine

The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer caryophylline to preparation of drugs for treating and/or preventing diabetes related diseases, and particularly relates to application of the alpinia oxyphylla monomer caryophylline to...

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Hauptverfasser: ZHANG JUNQING, HE PEIXIA, WANG YINGHUAN, ZHOU MINGYAN, ZHU ZHE, PAN YIPENG, LIAN XIUXIA, WANG GAO'AN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer caryophylline to preparation of drugs for treating and/or preventing diabetes related diseases, and particularly relates to application of the alpinia oxyphylla monomer caryophylline to preparation of drugs for treating and/or preventing diabetes related diseases. According to the invention, by constructing an IR-HepG2 cell model, the effect of caryophylline in improving IR and glycometabolism is explored. Results show that after different concentrations of caryophyllan are incubated by IR-HepG2 cells, the intake and consumption of glucose are remarkably improved, the balance of glucose inside and outside the cells is maintained, and it is proved that the monomeric caryophyllan, which is one of the four south drugs and is beneficial to intelligence, can play a role in reducing blood sugar by improving the IR effect; furthermore, it is creatively found that the effect is optimal when the administr