Oligonucleotide conjugates targeting transferrin receptors

Provided herein are conjugates comprising proteins that bind to transferrin receptors and oligonucleotides capable of modulating expression of a target gene or sequence, as well as methods of using the same. 本文提供包含结合转铁蛋白受体的蛋白质和能够调节靶基因或序列表达的寡核苷酸的缀合物，以及其使用方法。...

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Hauptverfasser:	BAKKER, SJALLE, SHAN LU, PARKER JOSHUA I, MAHON KATAR S, TANG RAYMOND-JIAHENG, WELLS ROBERT C, ESTRADA, ANTHONY, A, DEVOS SARAH L, DENNIS MARK S, KARIOLIS, MICHALIS, S, ZUCHERO JOY YU, NILEWSKI, LIZANNE, G, THAYER, MAI, B, CHEN HAY L
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	Provided herein are conjugates comprising proteins that bind to transferrin receptors and oligonucleotides capable of modulating expression of a target gene or sequence, as well as methods of using the same. 本文提供包含结合转铁蛋白受体的蛋白质和能够调节靶基因或序列表达的寡核苷酸的缀合物，以及其使用方法。