Application of hsa-miR-4712-3p as molecular marker and kit
The invention relates to a miRNA (micro Ribonucleic Acid) biomarker combination for diagnosing or assisting in screening a high altitude headache (HAH) susceptible person and a kit of the miRNA biomarker combination, and relates to the technical field of microRNA molecular detection. By extracting m...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a miRNA (micro Ribonucleic Acid) biomarker combination for diagnosing or assisting in screening a high altitude headache (HAH) susceptible person and a kit of the miRNA biomarker combination, and relates to the technical field of microRNA molecular detection. By extracting miRNA in plasma of HAH and a healthy control group for expression level detection and comparison, the result shows that compared with the healthy control group, hsa-miR-4712-3p expression of a HAH susceptible person in plasma and saliva specimens is remarkably up-regulated compared with the expression in the control group, the method has statistical significance in difference between the HAH susceptible person and the healthy control group, and the method has a good application prospect. The method has good diagnostic efficiency, is suitable for large-scale screening of HAH susceptible persons in plains, and prevents the onset risk of HAH after entering plateau.
本发明涉及本发明公开了一种用于诊断或辅助筛查高原头痛(high altitude headache,HAH) |
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