Application of hsa-miR-4712-3p as molecular marker and kit

The invention relates to a miRNA (micro Ribonucleic Acid) biomarker combination for diagnosing or assisting in screening a high altitude headache (HAH) susceptible person and a kit of the miRNA biomarker combination, and relates to the technical field of microRNA molecular detection. By extracting m...

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Hauptverfasser: ZHANG YINGJU, PAN JING, CAO JIUJIAN, LIU YAN, DAN ZHEN, XIE SHENWEI, SU LINHAN, HUANG HE, LI JIANXUE, HE DAN, HUANG JIANPING, KANG XUN, HUANG PEI, LIU DONGMEI, GUO YAN, WAN DONGJUN, ZHANG DONGMEI, CHEN PENGDE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a miRNA (micro Ribonucleic Acid) biomarker combination for diagnosing or assisting in screening a high altitude headache (HAH) susceptible person and a kit of the miRNA biomarker combination, and relates to the technical field of microRNA molecular detection. By extracting miRNA in plasma of HAH and a healthy control group for expression level detection and comparison, the result shows that compared with the healthy control group, hsa-miR-4712-3p expression of a HAH susceptible person in plasma and saliva specimens is remarkably up-regulated compared with the expression in the control group, the method has statistical significance in difference between the HAH susceptible person and the healthy control group, and the method has a good application prospect. The method has good diagnostic efficiency, is suitable for large-scale screening of HAH susceptible persons in plains, and prevents the onset risk of HAH after entering plateau. 本发明涉及本发明公开了一种用于诊断或辅助筛查高原头痛(high altitude headache,HAH)