Pirfenidone sustained release preparation as well as preparation method and application thereof

The invention discloses a pirfenidone sustained release preparation as well as a preparation method and application thereof. The pirfenidone sustained release preparation provided by the invention contains pirfenidone, a hydrogel material and a disintegrating agent, the hydrogel material is selected...

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Hauptverfasser: ZHOU ZILIN, BIAN CONG, XU PENGFEI, JANG BYOUNG-WOOK
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creator ZHOU ZILIN
BIAN CONG
XU PENGFEI
JANG BYOUNG-WOOK
description The invention discloses a pirfenidone sustained release preparation as well as a preparation method and application thereof. The pirfenidone sustained release preparation provided by the invention contains pirfenidone, a hydrogel material and a disintegrating agent, the hydrogel material is selected from the following group: hydroxy propyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, carrageenan, xanthan gum, guar gum, Arabic gum, polyvinyl acetate, carbomer, alginate, polyoxyethylene, methyl cellulose, carboxymethyl cellulose, povidone, chitosan or a combination thereof; the disintegrating agent is selected from the following group: cross-linked povidone, cross-linked sodium carboxymethyl cellulose, low-substituted hydroxy propyl cellulose, sodium carboxymethyl starch, cross-linked calcium carboxymethyl cellulose or a combination of the cross-linked povidone, the cross-linked sodium carboxymethyl cellulose, the low-substituted hydroxy propyl cellulose, the sodium carboxymethyl starch an
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pirfenidone sustained release preparation as well as preparation method and application thereof
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