Pirfenidone sustained release preparation as well as preparation method and application thereof

The invention discloses a pirfenidone sustained release preparation as well as a preparation method and application thereof. The pirfenidone sustained release preparation provided by the invention contains pirfenidone, a hydrogel material and a disintegrating agent, the hydrogel material is selected from the following group: hydroxy propyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, carrageenan, xanthan gum, guar gum, Arabic gum, polyvinyl acetate, carbomer, alginate, polyoxyethylene, methyl cellulose, carboxymethyl cellulose, povidone, chitosan or a combination thereof; the disintegrating agent is selected from the following group: cross-linked povidone, cross-linked sodium carboxymethyl cellulose, low-substituted hydroxy propyl cellulose, sodium carboxymethyl starch, cross-linked calcium carboxymethyl cellulose or a combination of the cross-linked povidone, the cross-linked sodium carboxymethyl cellulose, the low-substituted hydroxy propyl cellulose, the sodium carboxymethyl starch an