Monoclonal antibody specifically binding to GD2

The invention relates to the fields of biotechnology and medicine, in particular to a monoclonal antibody specifically bound with GD2 (ganglioside GD2) or an antigen binding fragment of the monoclonal antibody. The invention further relates to nucleic acids encoding said antibodies, expression vecto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	YAGIEV SERGEY ANATOLIEVICH, GRAEFENSTEIN, MICHAEL, A, CHERNYKH YEVGENIY SERGEEVICH, STOJAROVA ANNA KONSTANTINOVNA, SOLOVYEV, VALERY VLADIMIROVICH, KONDINSKAYA DMITRIY ALEKSANDROVICH, YAKOVLEV PAVEL ANDREEVICH, SAHAROVA, DARIYA KONSTANTINOVNA, SIJINA, VADIM, E, MOROZOV DMITRY VLADIMIROVICH
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the fields of biotechnology and medicine, in particular to a monoclonal antibody specifically bound with GD2 (ganglioside GD2) or an antigen binding fragment of the monoclonal antibody. The invention further relates to nucleic acids encoding said antibodies, expression vectors, host cells and methods for producing the same, methods for producing antibodies according to the invention, pharmaceutical compositions comprising antibodies according to the invention, pharmaceutical compositions comprising antibodies according to the invention and other therapeutically active compounds, and methods for preparing the same. The present invention relates to antibodies or pharmaceutical compositions thereof, methods for the treatment of diseases or disorders mediated by GD2, the use of antibodies or pharmaceutical compositions thereof for the treatment of diseases or disorders mediated by GD2, and the use of antibodies and other therapeutically active compounds for the treatment of diseases or di