Application of SULT2B1 gene

The invention discloses application of an SULT2B1 gene, and belongs to the field of molecular biology, the application of the SULT2B1 gene provided by the invention comprises the following steps: taking the SULT2B1 gene as a biological marker of colorectal cancer, and reducing the migration ability...

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Bibliographische Detailangaben
Hauptverfasser: LIU JIAN, CHE GANG, YIN JIE, WANG WANKUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of an SULT2B1 gene, and belongs to the field of molecular biology, the application of the SULT2B1 gene provided by the invention comprises the following steps: taking the SULT2B1 gene as a biological marker of colorectal cancer, and reducing the migration ability of colorectal cancer cells and the invasion ability of the colorectal cancer cells by reducing the expression level of the SULT2B1 gene. On the basis, the invention provides application of the SULT2B1 inhibitor to screening of colorectal cancer medicines and/or preparation of a medicine composition for treating colorectal cancer and/or preparation of a colorectal cancer diagnosis product. A novel molecular marker SULT2B1 gene for colorectal cancer is found for the first time, whether a subject suffers from colorectal cancer or not can be judged by detecting the expression level of SULT2B1 in colorectal tissue of the subject, the metastasis risk can be judged, and prognosis of a patient can be predicted, so that a c