Primer group and method for detecting deletion type thalassemia and application of primer group and method

The invention aims to provide a primer group and a method for detecting Chinese common deletion type thalassemia and application of the primer group and the method, and the primer group and the method can realize specific detection on--SEA,-alpha3.7,-alpha4.2 and--THAI and Chinese type G gamma + (A...

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Bibliographische Detailangaben
Hauptverfasser: XU YANTING, CHEN XIUXIA, LIANG DANJUN, GENG JUAN, YE XING, JUNG SO-KYUNG, CHEN BIXIAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention aims to provide a primer group and a method for detecting Chinese common deletion type thalassemia and application of the primer group and the method, and the primer group and the method can realize specific detection on--SEA,-alpha3.7,-alpha4.2 and--THAI and Chinese type G gamma + (A gamma delta beta) 0 mutation sites; the method has the advantages of high accuracy, high sensitivity, good repeatability, low cost, short detection period, visual result, no need of intervention of bioinformatics technology and the like; the defect that few deletion type thalassemia sites are detected at a time in the prior art is overcome, and the kit is suitable for being widely popularized; according to the method, the adaptability of a required sample is high, and peripheral blood and whole genome amplification products can be well detected; the kit is suitable for infants and people needing fertility, and can help subjects with suspected family history to screen pathogenic deficiency, evaluate pathogenic effic